| Product name | CTND2 Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from part region of human CTND2 protein |
| Host | Rabbit |
| Reactivity | Human,Mouse |
| Applications | WB,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | Catenin delta-2; Delta-catenin; GT24; Neural plakophilin-related ARM-repeat protein; NPRAP; Neurojungin |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 134kD |
| Storage buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | CTNND2 encodes an adhesive junction associated protein of the armadillo/beta-catenin superfamily and is implicated in brain and eye development and cancer formation. The protein encoded by this gene promotes the disruption of E-cadherin based adherens junction to favor cell spreading upon stimulation by hepatocyte growth factor. This gene is overexpressed in prostate adenocarcinomas and is associated with decreased expression of tumor suppressor E-cadherin in this tissue. This gene resides in a region of the short arm of chromosome 5 that is deleted in Cri du Chat syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| Gene ID | 1501 |
| Alternative | Catenin delta-2; Delta-catenin; GT24; Neural plakophilin-related ARM-repeat protein; NPRAP; Neurojungin |
| Others | The antibody detects endogenous levels of CTND2 protein |
| Accession | Q9UQB3 |
| Observed Band(KD) | 134 |
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