| Product name | CRM1 (Acetyl Lys568) Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from the Internal region of human CRM1 around the acetylation site of K568 |
| Host | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Applications | WB,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications. |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | XPO1; CRM1; Exportin-1; Exp1; Chromosome region maintenance 1 protein homolog |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 125kD |
| Storage buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | This cell-cycle-regulated gene encodes a protein that mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. Exportin 1 also regulates NFAT and AP-1. |
| Gene ID | 7514 |
| Alternative | XPO1; CRM1; Exportin-1; Exp1; Chromosome region maintenance 1 protein homolog |
| Others | Acetyl-CRM1 (K568) Polyclonal Antibody detects endogenous levels of CRM1 protein only when non-acetylation at K568. |
| Accession | O14980 |
| Observed Band(KD) | 125 |
Fig.1. Western Blot analysis of HepG2-UV, mouse brain cells using Acetyl-CRM1 (K568) Polyclonal Antibody. Antibody was diluted at 1:500. Secondary Antibody was diluted at 1:20000.
Fig.2. Western Blot analysis of HEPG2-UV cells using Acetyl-CRM1 (K568) Polyclonal Antibody diluted at 1:500. Secondary Antibody was diluted at 1:20000.
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