| Product name | CRLF1 Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from part region of human CRLF1 protein at amino acid sequence of 50-130 |
| Host | Rabbit |
| Reactivity | Human,Mouse |
| Applications | WB,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | Cytokine receptor-like factor 1; Cytokine-like factor 1; ZcytoR5 |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 46kD |
| Storage buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | CRLF1 (Cytokine Receptor Like Factor 1) is a Protein Coding gene. Diseases associated with CRLF1 include Cold-Induced Sweating Syndrome 1 and Crlf1-Related Cold-Induced Sweating Syndrome Including Crisponi Syndrome. Among its related pathways are Cytokine Signaling in Immune system and Innate Immune System. CRLF1 encodes a member of the cytokine type I receptor family. The protein forms a secreted complex with cardiotrophin-like cytokine factor 1 and acts on cells expressing ciliary neurotrophic factor receptors. The complex can promote survival of neuronal cells. Mutations in CRLF1 result in Crisponi syndrome and cold-induced sweating syndrome. |
| Gene ID | 9244 |
| Alternative | Cytokine receptor-like factor 1; Cytokine-like factor 1; ZcytoR5 |
| Others | The antibody detects endogenous levels of CRLF1 protein |
| Accession | O75462 |
| Observed Band(KD) | 46 |
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