| Product name | Collagen XI α1 Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from part region of human Collagen XI α1 protein |
| Host | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Applications | WB,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:10000-20000 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | Collagen alpha-1; XI chain |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 180kD |
| Storage buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | COL11A1 encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Mutations in this gene are associated with type II Stickler syndrome and with Marshall syndrome. A single-nucleotide polymorphism in COL11A1 is also associated with susceptibility to lumbar disc herniation. Multiple transcript variants have been identified for COL11A1. |
| Gene ID | 1301 |
| Alternative | Collagen alpha-1; XI chain |
| Others | This antibody detects endogenous levels of Collagen XI α1. |
| Accession | P12107 |
| Observed Band(KD) | 180 |
Fig.1. Western blot analysis of CACO2 lysate, antibody was diluted at 1:1000. HRP, Goat Anti-Rabbit IgG (Cat #: A21020) secondary antibody was diluted at 1:20000.
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