| Product name | CO3 Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from part region of human CO3 protein |
| Host | Rabbit |
| Reactivity | Human,Rat,Mouse |
| Applications | WB,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | Complement C3; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1 |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 182kD |
| Storage buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. Complement C3 is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in C3 are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients. |
| Gene ID | 718 |
| Alternative | Complement C3; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1 |
| Others | The antibody detects endogenous levels of CO3 protein |
| Accession | P01024 |
| Observed Band(KD) | 182 |
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