| Product name | CLH1 Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from part region of human CLH1 protein |
| Host | Rabbit |
| Reactivity | Human,Rat,Mouse, |
| Applications | WB,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | Clathrin heavy chain 1; Clathrin heavy chain on chromosome 17; CLH-17 |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 184kD |
| Storage buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Two different adapter protein complexes link the clathrin lattice either to the plasma membrane or to the trans-Golgi network. Acts as component of the TACC3/ch-TOG/clathrin complex proposed to contribute to stabilization of kinetochore fibers of the mitotic spindle by acting as inter-microtubule bridge (PubMed: 15858577, PubMed: 16968737, PubMed: 21297582). The TACC3/ch-TOG/clathrin complex is required for the maintenance of kinetochore fiber tension (PubMed: 23532825). Plays a role in early autophagosome formation (PubMed: 20639872). |
| Gene ID | 1213 |
| Alternative | Clathrin heavy chain 1; Clathrin heavy chain on chromosome 17; CLH-17 |
| Others | The antibody detects endogenous levels of CLH1 protein |
| Accession | Q00610 |
| Observed Band(KD) | 184 |
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