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Cleaved-SUMO-2/3 (G93) Polyclonal Antibody

Cleaved-SUMO-2/3 (G93) Polyclonal Antibody

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Specification

Product name Cleaved-SUMO-2/3 (G93) Polyclonal Antibody
Immunogen Synthesized peptide derived from the Internal region of human SUMO-2/3 at AA range: 20-100
Host Rabbit
Reactivity Human,Mouse,Rat
Applications WB,ELISA,CoIP
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000;ELISA 1:20000;IP 1:50-100;Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative SUMO2; SMT3A; SMT3H2; Small ubiquitin-related modifier 2; SUMO-2; HSMT3; SMT3 homolog 2; SUMO-3; Sentrin-2; Ubiquitin-like protein SMT3A; Smt3A

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Molecular weight 11kD
Storage buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background SUMO2 encodes small ubiquitin-like modifier 2 that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, small ubiquitin-like modifier 2 is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Numerous pseudogenes have been reported for SUMO2. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Gene ID 6613
Alternative SUMO2; SMT3A; SMT3H2; Small ubiquitin-related modifier 2; SUMO-2; HSMT3; SMT3 homolog 2; SUMO-3; Sentrin-2; Ubiquitin-like protein SMT3A; Smt3A
Others Cleaved-SUMO-2/3 (G93) Polyclonal Antibody detects endogenous levels of fragment of activated SUMO-2/3 protein resulting from cleavage adjacent to G93.
Accession P61956
Observed Band(KD) 11

Image & description

Fig. Western Blot analysis of various cells using Cleaved-SUMO-2/3 (G93) Polyclonal Antibody.

Fig. Western Blot analysis of various cells using Cleaved-SUMO-2/3 (G93) Polyclonal Antibody.

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