| Product name | Cleaved-KLK8 (V33) Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from the N-terminal region of human KLK8 at AA range: 30-110 |
| Host | Rabbit |
| Reactivity | Human,Rat,Mouse, |
| Applications | WB,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications. |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | KLK8; NRPN; PRSS19; TADG14; Kallikrein-8; hK8; Neuropsin; NP; Ovasin; Serine protease 19; Serine protease TADG-14; Tumor-associated differentially expressed gene 14 protein |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 24kD |
| Storage buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. KLK8 is one of the fifteen kallikrein subfamily members located in tandem in a gene cluster on chromosome 19. Kallikrein related peptidase 8 may be involved in proteolytic cascade in the skin and may serve as a biomarker for ovarian cancer. Alternate splicing of KLK8 results in multiple transcript variants encoding different isoforms. |
| Gene ID | 11202 |
| Alternative | KLK8; NRPN; PRSS19; TADG14; Kallikrein-8; hK8; Neuropsin; NP; Ovasin; Serine protease 19; Serine protease TADG-14; Tumor-associated differentially expressed gene 14 protein |
| Others | Cleaved-KLK8 (V33) Polyclonal Antibody detects endogenous levels of fragment of activated KLK8 protein resulting from cleavage adjacent to V33. |
| Accession | O60259 |
| Observed Band(KD) | 24 |
Fig. Western Blot analysis of various cells using Cleaved-KLK8 (V33) Polyclonal Antibody.
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