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CLCN1 Polyclonal Antibody

CLCN1 Polyclonal Antibody

Views(14) Publications(0) Catalog no(ABP58180)
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Specification

Product name CLCN1 Polyclonal Antibody
Immunogen Synthesized peptide derived from part region of human CLCN1 protein
Host Rabbit
Reactivity Human,Rat,Mouse,
Applications WB,ELISA
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Chloride channel protein 1; ClC-1; Chloride channel protein, skeletal muscle

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Molecular weight 108kD
Storage buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background CLCN1 (Chloride Voltage-Gated Channel 1) is a Protein Coding gene. Diseases associated with CLCN1 include Myotonia Congenita, Recessive and Myotonia Congenita, Dominant The protein encoded by CLCN1 regulates the electric excitability of the skeletal muscle membrane. Mutations in CLCN1 cause two forms of inherited human muscle disorders: recessive generalized myotonia congenita (Becker) and dominant myotonia (Thomsen). Alternative splicing results in multiple transcript variants.
Gene ID 1180
Alternative Chloride channel protein 1; ClC-1; Chloride channel protein, skeletal muscle
Others The antibody detects endogenous levels of CLCN1 protein
Accession P35523
Observed Band(KD) 108

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