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CLC14 Polyclonal Antibody

CLC14 Polyclonal Antibody

Views(11) Publications(0) Catalog no(ABP58172)
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Specification

Product name CLC14 Polyclonal Antibody
Immunogen Synthesized peptide derived from part region of human CLC14 protein
Host Rabbit
Reactivity Human,Mouse
Applications WB,ELISA
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative C-type lectin domain family 14 member A; Epidermal growth factor receptor 5; EGFR-5

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Molecular weight 53kD
Storage buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background CLEC14A encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. This family member plays a role in cell-cell adhesion and angiogenesis. It functions in filopodia formation, cell migration and tube formation. Due to its presence at higher levels in tumor endothelium than in normal tissue endothelium, it is considered to be a candidate for tumor vascular targeting. CLEC14A (C-Type Lectin Domain Containing 14A) is a Protein Coding gene. Among its related pathways are p70S6K Signaling and Apoptotic Pathways in Synovial Fibroblasts.
Gene ID 161198
Alternative C-type lectin domain family 14 member A; Epidermal growth factor receptor 5; EGFR-5
Others The antibody detects endogenous levels of CLC14 protein
Accession Q86T13
Observed Band(KD) 53

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