| Product name | CD88 Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from the N-terminal region of human CD88 |
| Host | Rabbit |
| Reactivity | Human,Rat,Mouse, |
| Applications | WB,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications. |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | C5AR1; C5AR; C5R1; C5a anaphylatoxin chemotactic receptor; C5a-R; C5aR; CD88 |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 39kD |
| Storage buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | OPRPN (opiorphin prepropeptide) encodes a member of the proline-rich protein family. The encoded protein has multiple proposed functions, including roles in pain suppression, penile erection, and protection of the eye surface. The QRFSR pentapeptide, known as opiorphin, is derived from the N-terminal of this protein. Opiorphin inhibits the enkephalin-inactivating peptidases neprilysin and aminopeptidase N, and this activity is thought to reduce sensitivity to painful stimuli by effecting enkephalin-related activation of opioid-dependent pathways. Opiorphin may also act as an anti-depressant. Alternative splicing results in multiple transcript variants. |
| Gene ID | 58503 |
| Alternative | C5AR1; C5AR; C5R1; C5a anaphylatoxin chemotactic receptor; C5a-R; C5aR; CD88 |
| Others | CD88 Polyclonal Antibody detects endogenous levels of CD88 protein. |
| Accession | P21730 |
| Observed Band(KD) | 39 |
Fig.1. Western blot analysis of Mouse-BRAIN RAT-SPLEEN lysis using C5AR1 antibody. Antibody was diluted at 1:1000. Secondary antibody (catalog#: A21020) was diluted at 1:20000.
Fig.2. Western Blot analysis of various cells using Antibody diluted at 1:1000. Secondary antibody (catalog#: A21020) was diluted at 1:20000.
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