| Product name | CD207 Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from the Internal region of human CD207 |
| Host | Rabbit |
| Reactivity | Human,Mouse |
| Applications | WB,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications. |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | CD207; CLEC4K; C-type lectin domain family 4 member K; Langerin; CD207 |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 38kD |
| Storage buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | C-type lectin domain family 4 member K encoded by CD207 is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity. |
| Gene ID | 50489 |
| Alternative | CD207; CLEC4K; C-type lectin domain family 4 member K; Langerin; CD207 |
| Others | CD207 Polyclonal Antibody detects endogenous levels of CD207 protein. |
| Accession | Q9UJ71 |
| Observed Band(KD) | 38 |
Fig. Western Blot analysis of K562 cells using CD207 Polyclonal Antibody. Secondary antibody (catalog#: A21020) was diluted at 1:20000.
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