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CCNL2 Polyclonal Antibody

CCNL2 Polyclonal Antibody

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Specification

Product name CCNL2 Polyclonal Antibody
Immunogen Synthesized peptide derived from part region of human CCNL2 protein at amino acid sequence of 400-480
Host Rabbit
Reactivity Human,Mouse,Rat
Applications WB,ELISA
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Cyclin-L2; Paneth cell-enhanced expression protein

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Molecular weight 57kD
Storage buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background The protein encoded by CCNL2 (Cyclin L2) belongs to the cyclin family. Through its interaction with several proteins, such as RNA polymerase II, splicing factors, and cyclin-dependent kinases, this protein functions as a regulator of the pre-mRNA splicing process, as well as in inducing apoptosis by modulating the expression of apoptotic and antiapoptotic proteins. Alternatively spliced transcript variants encoding different isoforms have been described for CCNL2. Diseases associated with CCNL2 include Star Syndrome.
Gene ID 81669
Alternative Cyclin-L2; Paneth cell-enhanced expression protein
Others The antibody detects endogenous levels of CCNL2 protein
Accession Q96S94
Observed Band(KD) 57

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