| Product name | Cadherin-16 Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from the C-terminal region of human Cadherin-16 at AA range: 750-830 |
| Host | Rabbit |
| Reactivity | Human,Mouse |
| Applications | WB,IHC,IF,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications. |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | CDH16; Cadherin-16; Kidney-specific cadherin; Ksp-cadherin |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 90kD |
| Storage buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | CDH16 is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with superfamily members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development. Alternatively spliced transcript variants encoding distinct isoforms have been identified. |
| Gene ID | 1014 |
| Alternative | CDH16; Cadherin-16; Kidney-specific cadherin; Ksp-cadherin |
| Others | Cadherin-16 Polyclonal Antibody detects endogenous levels of Cadherin-16 protein. |
| Accession | O75309 |
| Observed Band(KD) | 90 |
Fig.1. Western Blot analysis of various cells using Cadherin-16 Polyclonal Antibody diluted at 1:1000.
Fig.2. Western Blot analysis of A549 cells using Cadherin-16 Polyclonal Antibody diluted at 1:1000.
You must be logged in to post a review.
Reviews
There are no reviews yet.