| Product name | ATG10 Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from part region of human ATG10 protein at amino acid sequence of 1-50 |
| Host | Rabbit |
| Reactivity | Human,Mouse |
| Applications | IHC,IF,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-200;ELISA 1:10000-20000;IF 1:50-200 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | Ubiquitin-like-conjugating enzyme ATG10; Autophagy-related protein 10; APG10-like |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Storage buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | Autophagy is a process for the bulk degradation of cytosolic compartments by lysosomes. ATG10 is an E2-like enzyme involved in 2 ubiquitin-like modifications essential for autophagosome formation: aTG12 (MIM 609608)-ATG5 (MIM 604261) conjugation and modification of a soluble form of MAP-LC3 (MAP1LC3A; MIM 601242), a homolog of yeast Apg8, to a membrane-bound form (Nemoto et al. 2003 ATG10 (Autophagy Related 10) is a Protein Coding gene. Diseases associated with ATG10 include Anthracosis. Among its related pathways are Cellular Senescence (REACTOME) and Autophagy Pathway. |
| Gene ID | 83734 |
| Alternative | Ubiquitin-like-conjugating enzyme ATG10; Autophagy-related protein 10; APG10-like |
| Others | The antibody detects endogenous levels of ATG10 |
| Accession | Q9H0Y0 |
Fig.1. Immunohistochemical analysis of paraffin-embedded human-tonsil, antibody was diluted at 1:200.
Fig.2. Immunohistochemical analysis of paraffin-embedded human-tonsil, antibody was diluted at 1:200.
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