| Product name | ARHGEF10 Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from the Internal region of human ARHGEF10 at AA range: 310-390 |
| Host | Rabbit |
| Reactivity | Human,Monkey |
| Applications | WB,IHC,IF,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | ARHGEF10; KIAA0294; Rho guanine nucleotide exchange factor 10 |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 152kD |
| Storage buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | ARHGEF10 encodes a Rho guanine nucleotide exchange factor (GEF). Rho GEFs regulate the activity of small Rho GTPases by stimulating the exchange of guanine diphosphate (GDP) for guanine triphosphate (GTP) and may play a role in neural morphogenesis. Mutations in ARHGEF10 are associated with slowed nerve conduction velocity (SNCV). Alternative splicing results in multiple transcript variants. |
| Gene ID | 9639 |
| Alternative | ARHGEF10; KIAA0294; Rho guanine nucleotide exchange factor 10 |
| Others | ARHGEF10 Polyclonal Antibody detects endogenous levels of ARHGEF10 protein. |
| Accession | O15013 |
Fig. Western Blot analysis of various cells using ARHGEF10 Polyclonal Antibody.
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