| Product name | Aldose Reductase Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from the C-terminal region of human Aldose Reductase at AA range: 210-290 |
| Host | Rabbit |
| Reactivity | Human,Rat |
| Applications | WB,IHC,IF,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications. |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | AKR1B1; ALDR1; Aldose reductase; AR; Aldehyde reductase; Aldo-keto reductase family 1 member B1 |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 36kD |
| Storage buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | AKR1B1 encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member (aldo-keto reductase family 1 member B) catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database. |
| Gene ID | 231 |
| Alternative | AKR1B1; ALDR1; Aldose reductase; AR; Aldehyde reductase; Aldo-keto reductase family 1 member B1 |
| Others | Aldose Reductase Polyclonal Antibody detects endogenous levels of Aldose Reductase protein. |
| Accession | P15121 |
Fig.1. Western Blot analysis of various cells using Aldose Reductase Polyclonal Antibody.
Fig.2. Western Blot analysis of HuvEc cells using Aldose Reductase Polyclonal Antibody.
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