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AHNK Polyclonal Antibody

AHNK Polyclonal Antibody

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Specification

Product name AHNK Polyclonal Antibody
Immunogen Synthesized peptide derived from part region of human AHNK protein at amino acid sequence of 5720-5800
Host Rabbit
Reactivity Human
Applications IHC,IF
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-300;IF 1:50-200
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Neuroblast differentiation-associated protein AHNAK; Desmoyokin

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Molecular weight 647kD
Storage buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background The protein encoded by AHNAK is a large (700 kDa) structural scaffold protein consisting of a central domain with 128 aa repeats. The encoded protein may play a role in such diverse processes as blood-brain barrier formation, cell structure and migration, cardiac calcium channel regulation, and tumor metastasis. A much shorter variant encoding a 17 kDa isoform exists for this gene, and the shorter isoform initiates a feedback loop that regulates alternative splicing of AHNAKe.
Gene ID 79026
Alternative Neuroblast differentiation-associated protein AHNAK; Desmoyokin
Others The antibody detects endogenous levels of AHNK protein
Accession Q09666

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