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ADNP Polyclonal Antibody

ADNP Polyclonal Antibody

Views(4) Publications(0) Catalog no(ABP54339)
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Specification

Product name ADNP Polyclonal Antibody
Immunogen Synthesized peptide derived from the N-terminal region of human ADNP at AA rangle: 80-160
Host Rabbit
Reactivity Human,Mouse
Applications WB,IHC,IF,ELISA
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative ADNP; ADNP1; KIAA0784; Activity-dependent neuroprotector homeobox protein; Activity-dependent neuroprotective protein

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Molecular weight 124kD
Storage buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background Vasoactive intestinal peptide is a neuroprotective factor that has a stimulatory effect on the growth of some tumor cells and an inhibitory effect on others. ADNP encodes activity dependent neuroprotector homeobox that is upregulated by vasoactive intestinal peptide and may be involved in its stimulatory effect on certain tumor cells. The encoded protein contains one homeobox and nine zinc finger domains, suggesting that it functions as a transcription factor. This gene is also upregulated in normal proliferative tissues. Finally, the encoded protein may increase the viability of certain cell types through modulation of p53 activity. Alternatively spliced transcript variants encoding the same protein have been described.
Gene ID 23394
Alternative ADNP; ADNP1; KIAA0784; Activity-dependent neuroprotector homeobox protein; Activity-dependent neuroprotective protein
Others ADNP Polyclonal Antibody detects endogenous levels of ADNP protein.
Accession Q9H2P0

Image & description

Fig. Western Blot analysis of LOVO cells using ADNP Polyclonal Antibody.

Fig. Western Blot analysis of LOVO cells using ADNP Polyclonal Antibody.

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