| Product name | 4.1R (phospho Tyr660) Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from human 4.1R around the phosphorylation site of Y660 |
| Host | Rabbit |
| Reactivity | Human,Mouse |
| Applications | WB,IHC,IF,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | EPB41; E41P; Protein 4.1; P4.1; 4.1R; Band 4.1; EPB4.1 |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 60kD |
| Storage buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | The erythrocyte membrane protein band 4. encoded by EPB41, together with spectrin and actin, constitute the red cell membrane cytoskeletal network. This complex plays a critical role in erythrocyte shape and deformability. Mutations in this gene are associated with type 1 elliptocytosis (EL1). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
| Gene ID | 2035 |
| Alternative | EPB41; E41P; Protein 4.1; P4.1; 4.1R; Band 4.1; EPB4.1 |
| Others | Phospho-4.1R (Y660) Polyclonal Antibody detects endogenous levels of 4.1R protein only when phosphorylated at Y660. |
| Accession | P11171 |
Fig.1. Western Blot analysis of JK cells using Phospho-4.1R (Y660) Polyclonal Antibody.
Fig.2. Western Blot analysis of Jurkat cells using Phospho-4.1R (Y660) Polyclonal Antibody.
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