Descriptions:Interleukin 30 (IL-30) forms one chain of the heterodimeric cytokine called interleukin 27 (IL-27), thus it is also called IL27 p28, it predicts a molecular mass of 24.9 kDa. IL-30, the p28 subunit that forms IL-27 together with EBI3 and is also known as IL-27 p28 or IL-27A, has been considered a surrogate to represent IL-27. It was initially thought to be an IL-12-like cytokine promoting Th1 immunity because of its ability to induce T-bet and IL-12Rβ2 expression through STAT1 activation during Th1 differentiation.
Tags:IL-30
Descriptions:抑瘤素M (OSM)是一种糖蛋白,属于白细胞介素-6 (IL-6)细胞因子家族,该家族包括循环抑制因子、细胞集落刺激因子和白细胞介素-6。OSM是一种编码生长调节因子,可抑制多种肿瘤细胞系的增殖。它刺激AIDS-KS颗粒细胞的增殖。OSM调节细胞因子的产生,包括内皮细胞产生的IL-6、G-CSF和GM-CSF。OSM被许多认为是一种多效性细胞因子,通过特定的细胞表面摄取启动其生物活性。低亲和力含有gp130的蛋白质相似,现已被鉴定为高亲和力OSM受体的组成部分,可传递OSM信号。OSM还被证明在促炎和抗炎作用中发挥作用。OSM可能参与生物过程,包括胚胎发育、造血、通道重建、形成和破坏以及可能的中枢系统发育。
Tags:OSM
Descriptions:Bone morphogenetic proteins (BMPs) are a group of growth factors also known as cytokines and as metabologens. BMP-12 regulates chondrogenesis, bone morphogenesis, and neuron differentiation.
Applications:His tag
Tags:BMP-12
Descriptions:Caspase-2 Assay Kit (Colorimetric) provides a simple and convenient method for detecting the activity of caspase-2.
Tags:Caspase
Descriptions:Human IL-36γ protein, expressed in E. coli
Tags:IL-36γ
Descriptions:Fibroblast Growth Factors-10 (FGF-10) is a 23.4 kDa member of the fibroblast Growth Factors with 208 amino acid residues. FGF-10 is mainly secreted from endometrial stromal cells, fibroblasts, peritubular cells, leydig cells, muller glia cells. FGF-10 a multifunctional mesenchymal-epithelial signaling Growth Factors, can regulate embryonic development, cell proliferation and cell differentiation. It has been associated with cancer and human genetic disorders.
Tags:FGF-10
Descriptions:Vascular Endothelial Growth Factors 121 (VEGF121) is a truncated version of VEGF165, which produced in E. coli is a homodimer, non-glycosylated, polypeptide chain and having a molecular mass of 28.4 kDa. There is three different isoforms (120, 164 and 188 a.a.) found in mouse. VEGF 121 shows that lack basic heparin-binding regions and are freely diffusible. Mouse VEGF121 shares 98% identity with corresponding regions of rat, 89% with canine, feline, equine and porcine, and 87% with human, ovine and bovine VEGF, respectively.
Tags:VEGF121
Descriptions:Mouse IL-10 is the prototypic member of the IL-10 cytokine family,including IL-10,IL-19,IL-20,IL-22(IL-TIF),IL-24 and IL-26.
Applications:No tag
Tags:IL-10