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SLUG Polyclonal Antibody

SLUG Polyclonal Antibody

Views(189) Publications(0) Catalog no(ABP57198)
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Specification

Product name SLUG Polyclonal Antibody
Immunogen Recombinant Protein
Host Rabbit
Reactivity Human, Mouse, Rat
Applications IHC-P, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:1000), IHC-P (1:200-1:500).
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS, pH 7.4, containing 0.02% Sodium Azide as preservative and 50% Glycerol.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background SNAI2 (snail family transcriptional repressor 2) encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in SNAI2 may be associated with sporatic cases of neural tube defects.
Gene ID 6591
Others The antibody detects endogenous SLUG protein.
Accession O43623
Observed Band(KD) 30

Image & description

Fig.1. Immunohistochemical analysis of paraffin-embedded human breast caricnoma using SLUG Polyclonal Antibody.

Fig.1. Immunohistochemical analysis of paraffin-embedded human breast caricnoma using SLUG Polyclonal Antibody.

Fig.2. Western blot analysis of 1) MCF7, 2) Mouse Heart tissue, 3) Rat Heart tissue, 4) rat brain tissue using SLUG Polyclonal Antibody.

Fig.2. Western blot analysis of 1) MCF7, 2) Mouse Heart tissue, 3) Rat Heart tissue, 4) rat brain tissue using SLUG Polyclonal Antibody.

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