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Rat TNF-alpha protein

Rat TNF-alpha protein

Views(18) Publications(0) Catalog no(PRP1213)
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Specification

Product name Rat TNF-alpha protein
Sequence Amino acid sequence derived from Rat TNFα (P16599) (Leu80-Leu235) was expressed.
Protein length The recombinant RatTNF-alpha consists of 156 amino acids and has a predicted molecular mass of 17.2 kDa.
Preparation method E. coli
Purity >98% as determined by SDS-PAGE
Alternative TNF;TNFA;TNFSF2;DIF ;Tumor Necrosis Factor ;Tumor Necrosis Factor Ligand Superfamily Member;Tumor Necrosis Factor (TNF Superfamily, Member 2) ;Tumor Necrosis Factor Ligand 1F ;Tumor Necrosis Factor-Alpha ;TNF Superfamily, Member 2 ;TNLG1F 3;TNF 5

Product Properties

Formulation Lyophilized from sterile 20 mM tris 50 mM NaCl, pH 8.0.
Features & Benefits Endotoxin: <0.1 EU per µg of the protein as determined by the LAL method.
Molecular weight 17.2 kDa
Usage notes Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized Rat TNF-alpha protein using the buffer we provided not less than 100 µg/mL, which can then be further diluted to other aqueous solutions.
Storage instructions Lyophilized Rat TNFα protein product should be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Shipping The product is shipped at ambient temperature.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. Two receptors, TNF-R1 (TNF receptor type 1; CD120a; p55/60) and TNF-R2 (TNF receptor type 2; CD120b; p75/80), bind to TNF-alpha. TNF-alpha protein is produced mainly by macrophages, and large amounts of this cytokine are released in response to lipopolysaccharide, other bacterial products, and Interleukin-1 (IL-1). TNF-alpha is involved in fighting against the tumorigenesis, thus, is regarded as a molecular insight in cancer treatment.
Gene ID 24835
Alternative TNF;TNFA;TNFSF2;DIF ;Tumor Necrosis Factor ;Tumor Necrosis Factor Ligand Superfamily Member;Tumor Necrosis Factor (TNF Superfamily, Member 2) ;Tumor Necrosis Factor Ligand 1F ;Tumor Necrosis Factor-Alpha ;TNF Superfamily, Member 2 ;TNLG1F 3;TNF 5
Accession P16599

Image & description

Fig.SDS-PAGE analysis of Rat TNF-alpha protein.

Fig.SDS-PAGE analysis of Rat TNF-alpha protein.

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