Login Register
English
0

Cart

$ 0

PDGFRα Mouse Monoclonal Antibody (4G11)

PDGFRα Mouse Monoclonal Antibody (4G11)

Views(28) Publications(0) Catalog no(ABM40335)
Datasheet Print Share Email Share
  • Specification
  • FAQ
  • Publications(0)
  • Comments(0)

Specification

Product name PDGFRα Mouse Monoclonal Antibody (4G11)
Immunogen Synthetic Peptide of PDGFRα at AA range of 1010-1090
Host Mouse
Reactivity Human, Mouse, Rat
Applications IHC-P
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:200).
Clonality Monoclonal
Preparation method The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen
Alternative PDGFRA

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background PDGFRA (platelet derived growth factor receptor alpha) encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that PDGFRA plays a role in organ development, wound healing, and tumor progression. Mutations in PDGFRA have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.
Gene ID 5156
Alternative PDGFRA
Others PDGFRα protein detects endogenous levels of PDGFRA.
Accession P16234
Observed Band(KD) 180

Image & description

Fig.1. Immunohistochemical analysis of paraffin-embedded Rat Skin Tissue using PDGFR a Mouse mAb diluted at 1:200.

Fig.1. Immunohistochemical analysis of paraffin-embedded Rat Skin Tissue using PDGFR a Mouse mAb diluted at 1:200.

Fig.2. Immunohistochemical analysis of paraffin-embedded Human Skin Tissue using PDGFR a Mouse mAb diluted at 1:200.

Fig.2. Immunohistochemical analysis of paraffin-embedded Human Skin Tissue using PDGFR a Mouse mAb diluted at 1:200.

This product has been cited in0publications

Reviews

There are no reviews yet.

Be the first to review “PDGFRα Mouse Monoclonal Antibody (4G11)”