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Nrf2 Rabbit Polyclonal Antibody

Nrf2 Rabbit Polyclonal Antibody

Views(315) Publications(0) Catalog no(ABP57575)
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Specification

Product name Nrf2 Rabbit Polyclonal Antibody
Immunogen Recombinant Protein of Nrf2
Host Rabbit
Reactivity Human, Mouse, Rat
Applications IHC-P
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:50-1:200).
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
Alternative Nuclear factor erythroid 2-related factor 2; NF-E2-related factor 2; NFE2-related factor 2; HEBP1; Nuclear factor, erythroid derived 2, like 2

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS, pH 7.4, containing 0.02% Sodium Azide as preservative and 50% Glycerol.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background NFE2L2 (nuclear factor, erythroid 2 like 2) encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been characterized for NFE2L2.
Gene ID 4780
Alternative Nuclear factor erythroid 2-related factor 2; NF-E2-related factor 2; NFE2-related factor 2; HEBP1; Nuclear factor, erythroid derived 2, like 2
Others The antibody detects endogenous Nrf2 protein.
Accession Q16236
Observed Band(KD) 75-100

Image & description

Fig.1. Immunohistochemical analysis of paraffin-embedded Human Lung Carcinoma Tissue using Nrf2 Rabbit pAb diluted at 1:500.

Fig.1. Immunohistochemical analysis of paraffin-embedded Human Lung Carcinoma Tissue using Nrf2 Rabbit pAb diluted at 1:500.

Fig.2. Immunohistochemical analysis of paraffin-embedded Human Kidney Tissue using Nrf2 Rabbit pAb diluted at 1:500.

Fig.2. Immunohistochemical analysis of paraffin-embedded Human Kidney Tissue using Nrf2 Rabbit pAb diluted at 1:500.

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