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NF-κB p65 Polyclonal Antibody

NF-κB p65 Polyclonal Antibody

Views(3779) Publications(2) Catalog no(ABP57495)
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Specification

Product name NF-κB p65 Polyclonal Antibody
Immunogen Synthetic Peptide of NF-κB p65
Host Rabbit
Reactivity Human, Mouse, Rat
Applications ELISA, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000-1:20000).
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Alternative v-rel reticuloendotheliosis viral oncogene homolog A (avian)

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of the gene, RELA. Four transcript variants encoding different isoforms have been found for RELA.
Gene ID 5970
Alternative v-rel reticuloendotheliosis viral oncogene homolog A (avian)
Others NF-κB p65 Polyclonal Antibody detects endogenous levels of NF-κB p65.
Accession Q04206
Observed Band(KD) 60

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