Login Register
English
0

Cart

$ 0

Neuregulin-1 Polyclonal Antibody

Neuregulin-1 Polyclonal Antibody

Views(54) Publications(0) Catalog no(ABP53261)
Datasheet Print Share Email Share
  • Specification
  • FAQ
  • Publications(0)
  • Comments(0)

Specification

Product name Neuregulin-1 Polyclonal Antibody
Immunogen Synthesized peptide derived from the Internal region of human Neuregulin-1
Host Rabbit
Reactivity Human, Mouse, Rat
Applications ELISA, IHC-P, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Alternative NRG1; GGF; HGL; HRGA; NDF; SMDF; Pro-neuregulin-1, membrane-bound isoform; Pro-NRG1

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background Pro-neuregulin-1, membrane-bound isoform encoded by NRG1 is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD).
Gene ID 3084
Alternative NRG1; GGF; HGL; HRGA; NDF; SMDF; Pro-neuregulin-1, membrane-bound isoform; Pro-NRG1
Others Neuregulin-1 Polyclonal Antibody detects endogenous levels of Neuregulin-1 protein.
Accession Q02297
Observed Band(KD) 70

Image & description

Fig.1. Western Blot analysis of hela, HBE cells using Neuregulin-1 Polyclonal Antibody. Secondary antibody (catalog#: A21020) was diluted at 1:20000.

Fig.1. Western Blot analysis of hela, HBE cells using Neuregulin-1 Polyclonal Antibody. Secondary antibody (catalog#: A21020) was diluted at 1:20000.

Fig.2. Immunohistochemical analysis of paraffin-embedded rat-kidney, antibody was diluted at 1:100.

Fig.2. Immunohistochemical analysis of paraffin-embedded rat-kidney, antibody was diluted at 1:100.

Fig.3. Immunohistochemical analysis of paraffin-embedded rat-kidney, antibody was diluted at 1:100.

Fig.3. Immunohistochemical analysis of paraffin-embedded rat-kidney, antibody was diluted at 1:100.

This product has been cited in0publications

Reviews

There are no reviews yet.

Be the first to review “Neuregulin-1 Polyclonal Antibody”