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Product name MQAE
CAS Number 162558-52-3
Molecular Formula C14H16BrNO3
Alternative N-(Ethoxycarbonylmethyl)-6-methoxyquinolinium bromide

Product Properties

Formulation White solid
Features & Benefits • MQAE has high water solubility and membrane permeability.
• MQAE with bromide ion as a counteranion has fluorescence excitation at 350 nm and emission at 460 nm.
• The fluorescent intensity of MQAE decreases in proportion to the chloride increase in cells.
• Chloride ion concentrations less than 50 mM may be monitored without being affected by pH changes.
Molecular weight 326.19
Usage notes • The recommended concentration of stock solution is 10 μM/L. It’s soluble in buffer which do not contain Cl-.
• Factors influencing the titer of the product mainly includes the temperature, ionic strength, viscosity, protein, etc.
Storage instructions Store at +4°C. The product can be stored for up to 12 months. Protect from light.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background MQAE (N-(Ethoxycarbonylmethyl)-6-methoxyquinolinium bromide) is an improved chloride indicator that has greater sensitivity to chloride (Ksv= 200M-1) than SPQ (Ksv=118 M-1) and higher fluorescence quantum yield. The ester group of MQAE may slowly hydrolyze inside cells, resulting in a change in its fluorescence response.
Alternative N-(Ethoxycarbonylmethyl)-6-methoxyquinolinium bromide

Image & description

Fig. MQAE structure formula

Fig. MQAE structure formula

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