Login Register
English
0

Cart

$ 0

Mouse BMP-2 protein

Mouse BMP-2 protein

Views(231) Publications(0) Catalog no(PRP110126)
Datasheet Print Share Email Share
  • Specification
  • FAQ
  • Publications(0)
  • Comments(0)

Specification

Product name Mouse BMP-2 protein
Sequence Amino acid sequence derived from mature form of human BMP2 (NP_001191.1) (Gln283-Arg396) was expressed. The mature form sequences of human, mouse, rat, rhesus and canine BMP2 are identical.
Activity Measured by its ability to induce alkaline phosphatase production by MC3T3-E1 mouse osteoblastic cells. The ED50 for this effect is typically 0.5-2 μg/ml.
Protein length The recombinant human BMP2 monomer consists of 115 amino acids and has a predicted molecular mass of 13 kDa.
Preparation method E. coli
Purity > 95 % as determined by SDS-PAGE
Alternative BDA2; BDA2A; BMP-2; BMP2A; Bone morphogenetic protein 2; BMP2

Product Properties

Formulation Lyophilized from sterile 30 % CAN, 0.1 % TFA, pH 2.9.
Molecular weight 13 kDa
Usage notes Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized Mouse BMP-2 protein in sterile ddH2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
Storage instructions Lyophilized Mouse BMP-2 protein product should be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Shipping The product is shipped at ambient temperature.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background BMP-2 protein, like other bone morphogenetic proteins, plays an important role in the development of bone and cartilage. BMP-2 protein is involved in the hedgehog pathway, TGF beta signaling pathway, and cytokine-cytokine receptor interaction. BMP-2 and BMP-7 are osteogenic BMPs that have been demonstrated to potently induce osteoblast differentiation in a variety of cell types. BMP-2, BMP-4 and BMP-7 are known to be of major importance in bone formation and repair. In cancerous tissues BMP-2 protein may play an important role in the progression of glioma.
Gene ID 650
Alternative BDA2; BDA2A; BMP-2; BMP2A; Bone morphogenetic protein 2; BMP2
Accession NP_001191.1

Image & description

Fig.SDS-PAGE analysis of Mouse BMP-2 protein.

Fig.SDS-PAGE analysis of Mouse BMP-2 protein.

This product has been cited in0publications

Reviews

There are no reviews yet.

Be the first to review “Mouse BMP-2 protein”