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KOR-1 Polyclonal Antibody

KOR-1 Polyclonal Antibody

Views(43) Publications(0) Catalog no(ABP53397)
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Specification

Product name KOR-1 Polyclonal Antibody
Immunogen Synthesized peptide derived from mouse KOR-1 around the non-phosphorylation site of S369
Host Rabbit
Reactivity Mouse, Rat
Applications ELISA, IHC-P
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Alternative OPRK1; OPRK; Kappa-type opioid receptor; K-OR-1; KOR-1

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background OPRK1 encodes an opioid receptor, which is a member of the 7 transmembrane-spanning G protein-coupled receptor family. It functions as a receptor for endogenous ligands, as well as a receptor for various synthetic opioids. Ligand binding results in inhibition of adenylate cyclase activity and neurotransmitter release. This opioid receptor plays a role in the perception of pain and mediating the hypolocomotor, analgesic and aversive actions of synthetic opioids. Variations in this gene have also been associated with alcohol dependence and opiate addiction. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.
Gene ID 4986
Alternative OPRK1; OPRK; Kappa-type opioid receptor; K-OR-1; KOR-1
Others KOR-1 Polyclonal Antibody detects endogenous levels of KOR-1 protein.
Accession P41145
Observed Band(KD) 42

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