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KIR2.1 Polyclonal Antibody

KIR2.1 Polyclonal Antibody

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Specification

Product name KIR2.1 Polyclonal Antibody
Immunogen Synthesized peptide derived from the Internal region of human KIR2.1 at AA range: 50-130
Host Rabbit
Reactivity Human, Rat
Applications ELISA, IHC-P, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Alternative KCNJ2; IRK1; Inward rectifier potassium channel 2; Cardiac inward rectifier potassium channel; Inward rectifier K(+) channel Kir2.1; IRK-1; hIRK1; Potassium channel; inwardly rectifying subfamily J member 2

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. Inward rectifier potassium channel 2 encoded by KCNJ2 is an integral membrane protein and inward-rectifier type potassium channel. Inward rectifier potassium channel 2, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Mutations in this gene have been associated with Andersen syndrome, which is characterized by periodic paralysis, cardiac arrhythmias, and dysmorphic features.
Gene ID 3759
Alternative KCNJ2; IRK1; Inward rectifier potassium channel 2; Cardiac inward rectifier potassium channel; Inward rectifier K(+) channel Kir2.1; IRK-1; hIRK1; Potassium channel; inwardly rectifying subfamily J member 2
Others KIR2.1 Polyclonal Antibody detects endogenous levels of KIR2.1 protein.
Accession P63252
Observed Band(KD) 48

Image & description

Fig. Western Blot analysis of various cells using KIR2.1 Polyclonal Antibody diluted at 1:500.

Fig. Western Blot analysis of various cells using KIR2.1 Polyclonal Antibody diluted at 1:500.

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