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IRF-3 Polyclonal Antibody

IRF-3 Polyclonal Antibody

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Product name IRF-3 Polyclonal Antibody
Immunogen Synthesized peptide derived from human IRF-3 around the non-phosphorylation site of S396
Host Rabbit
Reactivity Human, Mouse, Rat
Applications ELISA, IHC-P, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Alternative IRF3; Interferon regulatory factor 3; IRF-3

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background IRF3 encodes a member of the interferon regulatory transcription factor (IRF) family. Interferon regulatory factor 3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene ID 3661
Alternative IRF3; Interferon regulatory factor 3; IRF-3
Others IRF-3 Polyclonal Antibody detects endogenous levels of IRF-3 protein.
Accession Q14653
Observed Band(KD) 47

Image & description

Fig. Western Blot analysis of various cells using IRF-3 Polyclonal Antibody diluted at 1:500.

Fig. Western Blot analysis of various cells using IRF-3 Polyclonal Antibody diluted at 1:500.

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