Login Register
English
0

Cart

$ 0

Integrin β4 Polyclonal Antibody

Integrin β4 Polyclonal Antibody

Views(96) Publications(0) Catalog no(ABP53199)
Datasheet Print Share Email Share
  • Specification
  • FAQ
  • Publications(0)
  • Comments(0)

Specification

Product name Integrin β4 Polyclonal Antibody
Immunogen Synthesized peptide derived from the Internal region of human Integrin β4
Host Rabbit
Reactivity Human, Mouse, Rat
Applications ELISA, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Alternative ITGB4; Integrin beta-4; GP150; CD104

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. ITGB4 encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Gene ID 3691
Alternative ITGB4; Integrin beta-4; GP150; CD104
Others Integrin β4 Polyclonal Antibody detects endogenous levels of Integrin β4 protein.
Accession P16144
Observed Band(KD) 200

Image & description

Fig. Western Blot analysis of PC12 cells using Integrin β4 Polyclonal Antibody. Secondary antibody (catalog#: A21020) was diluted at 1:20000.

Fig. Western Blot analysis of PC12 cells using Integrin β4 Polyclonal Antibody. Secondary antibody (catalog#: A21020) was diluted at 1:20000.

This product has been cited in0publications

Reviews

There are no reviews yet.

Be the first to review “Integrin β4 Polyclonal Antibody”