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Human FGF21 protein

Human FGF21 protein

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Specification

Product name Human FGF21 protein
Sequence Amino acid sequence derived from Human FGF21(Q9NSA1)(His29-Ser209) was expressed.
Protein length The recombinant human FGF21 consists of 181 amino acids and migrates with an apparent molecular mass of 19.4 kDa as estimated in SDS-PAGE under reducing conditions.
Preparation method E. coli
Purity ≥ 98 % as determined by SDS-PAGE
Alternative Fibroblast Growth Factor 21; FGF-21; FGF21

Product Properties

Formulation Lyophilized from sterile 20 mM Tris, 150 mM NaCl pH 8.0.
Molecular weight 19.4 kDa
Usage notes Always centrifuge tubes before opening . It is recommended to centrifuge at 12000 rpm for 1 minute.Then reconstitute the lyophilized Human FGF21 protein using the buffer we provided not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
Storage instructions Lyophilized Human FGF21 proteinshould be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.131% HSA or BSA). Please prevent freeze-thaw cycles.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background Fibroblast Growth Factor 21 (FGF21) is a growth factor that belongs to the FGF family. Proteins of this family possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGFs act through a family of four FGF receptors. Binding is complicated and requires both interaction of the FGF molecule with an FGF receptor and binding to heparin through an heparin binding domain. Endocrine FGFs lack a heparin binding domain and thus can be released into the circulation. FGF21 action through one of the FGF21 receptors thus requires interaction with a co-receptor, designated β-klotho.
Gene ID 26291
Alternative Fibroblast Growth Factor 21; FGF-21; FGF21
Accession Q9NSA1

Image & description

Fig. SDS-PAGE analysis of Human FGF21 protein.

Fig. SDS-PAGE analysis of Human FGF21 protein.

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