Product Information

• Product name

  Human CD7/GP40 protein, His tag (Animal-Free)

• Sequence

  Amino acid sequence derived from human CD7 protein (NP_006128.1，Met 1-Pro 180) was expressed with a polyhistidine tag at the C-terminus.

• Protein length

  The recombinant human CD7/GP40 protein consists of 161 amino acids and predicts a molecular mass of 18 kD.The apparent molecular mass of the human CD7 is approximately 25-35 kDa in SDS-PAGE under reducing conditions due to glycosylation.

• Preparation method

  HEK293 Cells

• Purity

  >95% as determined by SDS-PAGE

Fig.SDS-PAGE analysis of Human CD7/GP40 protein

Product Properties

• Formulation

  0.22 µm filtered protein solution is in PBS, pH 7.4.

• Features & Benefits

  Endotoxin: <0.1 EU per μg of the protein as determined by the LAL method.

• Molecular weight

  18 kDa

• Usage notes

  Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized human CD7/GP40 protein using the buffer we provided not less than 100 µg/mL, which can then be further diluted to other aqueous solutions.

• Storage instructions

  Lyophilized human CD7/GP40 protein product should be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

• Shipping

  The product is shipped at ambient temperature.

• Precautions

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

• Background

  The CD7 antigen is a member of the immunoglobulin superfamily that expresses on the surface of all thymocytes, a majority of mature T cells, and also natural killer cells. Interestingly, under physiological and different pathological conditions, the loss of CD7 antigen occurred in the subset of CD4+ memory T cells. The functions of the cell membrane CD7 antigen have been investigated in human mature T and NK cells, showing the direct involvement of this molecule in multiple effector functions related with activation, proliferation, production of cytokines and modification of adhesion properties. The CD7 glycoprotein is not only expressed by mature lymphoid cells, but also by early hematopoietic progenitors and several types of leukemias, suggesting a role of CD7 during hematopoiesis.

• Gene ID

  924

• Alternative names

  CD7 Molecule;T-Cell Leukemia Antigen;T-Cell Antigen CD7;TP41;T-Cell Surface Antigen Leu-9;CD7 Antigen (P41);P41 Protein;LEU-9;Tp40;CD7 Antigen 4;CD7

• Accession

  P09564