| Product name | Human CD24 protein, hFc tag (Animal-Free) |
| Sequence | Amino acid sequence derived from human CD24 (NP_037362.1) (Met 1-Gly 59) was expressed with the Fc region of human IgG1 at the C-terminus. |
| Protein length | The recombinant human CD24 consists of 270 amino acids and predicts a molecular mass of 29.7 KD. It migrates as an approximately 45-55 KD band in SDS-PAGE under reducing conditions due to glycosylation. |
| Preparation method | HEK293 Cells |
| Purity | >95% as determined by SDS-PAGE |
| Alternative | Signal transducer CD24; Small cell lung carcinoma cluster 4 antigen; CD24; CD24A |
| Formulation | Lyophilized from sterile PBS, pH 7.4. |
| Features & Benefits | Endotoxin: < 0.1 EU per µg of the protein as determined by the LAL method. |
| Molecular weight | 29.7 KD |
| Usage notes | Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized Human CD24 protein using the buffer we provided not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. |
| Storage instructions | Lyophilized Human CD24 protein, hFc tag (Animal-Free)should be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.23% HSA or BSA). Please prevent freeze-thaw cycles. |
| Shipping | The product is shipped at ambient temperature. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | The cluster of differentiation (CD) system is commonly used as cell markers in immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 32 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 24, also known as signal transducer CD24 or heat stable antigen CD24 (HSA), is a mucin-type glycosylphosphatidylinositol-linked glycoprotein expressed on the surface of B-cells, differentiating neuroblasts and many tumors. May have a pivotal role in cell differentiation of different cell types. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Modulates B-cell activation responses. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells. In association with SIGLEC10 may be involved in the selective suppression of the immune response to danger-associated molecular patterns (DAMPs) such as HMGB1, HSP70 and HSP90. Plays a role in the control of autoimmunity. |
| Gene ID | 100133941 |
| Alternative | Signal transducer CD24; Small cell lung carcinoma cluster 4 antigen; CD24; CD24A |
| Accession | P25063-1 |
Fig. SDS-PAGE analysis of Human CD24 protein, hFc tag.
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1.The species of antibody reactivity should be the sample species that can be matched normally after Abbkine R&D experts have passed strict scientific verification. If your sample is not within the range of reactivity, in order to improve the efficiency and results of your experiment, it is not suggested to try other species. Otherwise, it may lead to sample mismatch and affect the effect of your experiment.
2.Please aliquot the antibody received as soon as possible and store it at -20℃, avoid repeated freezing and thawing, and use it within one year.
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