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Human CD155/PVR protein, His tag (Animal-Free)

Human CD155/PVR protein, His tag (Animal-Free)

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Specification

Product name Human CD155/PVR protein, His tag (Animal-Free)
Sequence Amino acid sequence derived from human CD155 (NP_006496.3) (Met1-Asn343) was expressed with a 6 His tag at the C-terminus.
Protein length The recombinant human CD155 consists of 329 amino acids and predicts a molecular mass of 35.9 KD. It migrates as an approximately 53-70 KD band in SDS-PAGE under reducing conditions due to glycosylation.
Preparation method HEK293 Cells
Purity >95% as determined by SDS-PAGE
Alternative Poliovirus Receptor; Nectin-Like Protein 5; NECL-5; CD155; PVR; PVS

Product Properties

Formulation Lyophilized from sterile PBS, pH 7.4.
Features & Benefits Endotoxin: < 1.0 EU per µg of the protein as determined by the LAL method.
Molecular weight 35.9 KD
Usage notes Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized Human CD155/PVR protein using the buffer we provided not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.
Storage instructions Lyophilized Human CD155 protein product should be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Shipping The product is shipped at ambient temperature.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background CD155 is a transmembrane adhesion protein that belongs to the immunoglobulin superfamily. It possesses three immunoglobulin-like domains, a transmembrane domain, and the intracellular domain. CD155 is encoded by eight exons and differential mRNA splicing results in four isoforms named PVRα, PVRβ, PVRγ, and PVRδ. CD155 may assist in an efficient humoral immune response generated within the intestinal immune system. It has been demonstrated that CD155 can be recognized and bond by DNAM-1 and CD96 which promote the adhesion, migration and NK-cell killing, and thus efficiently prime cell-mediated tumor-specific immunity.
Gene ID 5817
Alternative Poliovirus Receptor; Nectin-Like Protein 5; NECL-5; CD155; PVR; PVS
Accession P15151

Image & description

Fig. SDS-PAGE analysis of Human CD155/PVR protein, His tag.

Fig. SDS-PAGE analysis of Human CD155/PVR protein, His tag.

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