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HP-1α Mouse Monoclonal Antibody (2G2)

HP-1α Mouse Monoclonal Antibody (2G2)

Views(137) Publications(0) Catalog no(ABM0084)
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Specification

Product name HP-1α Mouse Monoclonal Antibody (2G2)
Immunogen Recombinant Protein of HP-1α
Host Mouse
Reactivity Human, Mouse, Rat
Applications IHC-P, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:50-1:300).
Clonality Monoclonal
Preparation method The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen
Alternative Chromobox protein homolog 5; Antigen p25; Heterochromatin protein 1 homolog alpha; HP1 alpha

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Molecular weight 22 KD
Storage buffer PBS, pH 7.4, containing 0.02% Sodium Azide as preservative and 50% Glycerol.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background Heterochromatin protein 1 (HP1) is a family of heterochromatic adaptor molecules involved in both gene silencing and higher order chromatin structure. All three HP1 family members (α, β, and γ) are primarily associated with centromeric heterochromatin; however, HP1β and γ also localize to euchromatic sites in the genome. HP1 proteins are approximately 25 kDa in size and contain a conserved amino-terminal chromodomain, followed by a variable hinge region and a conserved carboxy-terminal chromoshadow domain.
Gene ID 23468
Alternative Chromobox protein homolog 5; Antigen p25; Heterochromatin protein 1 homolog alpha; HP1 alpha
Others The antibody detects endogenous HP-1α protein.
Accession P45973

Image & description

Fig.1. Immunohistochemical analysis of paraffin-embedded Human Placenta Tissue using HP-1α Mouse mAb diluted at 1:500.

Fig.1. Immunohistochemical analysis of paraffin-embedded Human Placenta Tissue using HP-1α Mouse mAb diluted at 1:500.

Fig.2. Immunohistochemical analysis of paraffin-embedded Human Placenta Tissue using HP-1α Mouse mAb diluted at 1:500.

Fig.2. Immunohistochemical analysis of paraffin-embedded Human Placenta Tissue using HP-1α Mouse mAb diluted at 1:500.

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