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Histone H2A.X (Phospho Tyr142) Polyclonal Antibody

Histone H2A.X (Phospho Tyr142) Polyclonal Antibody

Views(42) Publications(0) Catalog no(ABP50243)
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Specification

Product name Histone H2A.X (Phospho Tyr142) Polyclonal Antibody
Immunogen Synthetic Peptide
Host Rabbit
Reactivity Human, Mouse, Rat
Applications WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:1000-1:2000).
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen
Alternative H2AFX; H2AX; Histone H2A.x; H2a/x

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS, pH 7.4, containing 0.02% Sodium Azide as preservative and 50% Glycerol.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. H2AFX encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.
Gene ID 3014
Alternative H2AFX; H2AX; Histone H2A.x; H2a/x
Others The antibody detects endogenous Histone H2A.X (Phospho Tyr142) protein.
Accession P16104
Observed Band(KD) 15

Image & description

Fig. Western blot analysis of extracts from Hela cells, 1:2000. Secondary antibody was diluted at 1:20000.

Fig. Western blot analysis of extracts from Hela cells, 1:2000. Secondary antibody was diluted at 1:20000.

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