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HDAC6 Polyclonal Antibody

HDAC6 Polyclonal Antibody

Views(14) Publications(0) Catalog no(ABP51505)
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Specification

Product name HDAC6 Polyclonal Antibody
Immunogen Synthesized peptide derived from human HDAC6 around the non-phosphorylation site of S22
Host Rabbit
Reactivity Human, Mouse
Applications ELISA, IF, IHC-P, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Alternative HDAC6; KIAA0901; JM21; Histone deacetylase 6; HD6

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. Histone deacetylase 6 encoded by HDAC6 belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. Histone deacetylase 6 possesses histone deacetylase activity and represses transcription.
Gene ID 10013
Alternative HDAC6; KIAA0901; JM21; Histone deacetylase 6; HD6
Others HDAC6 Polyclonal Antibody detects endogenous levels of HDAC6 protein.
Accession Q9UBN7
Observed Band(KD) 131

Image & description

Fig. Western Blot analysis of various cells using HDAC6 Polyclonal Antibody diluted at 1:1000.

Fig. Western Blot analysis of various cells using HDAC6 Polyclonal Antibody diluted at 1:1000.

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