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HDAC1 Polyclonal Antibody

HDAC1 Polyclonal Antibody

Views(21) Publications(0) Catalog no(ABP51499)
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Specification

Product name HDAC1 Polyclonal Antibody
Immunogen Synthesized peptide derived from human HDAC1 around the non-phosphorylation site of S421
Host Rabbit
Reactivity Human, Mouse, Rat
Applications ELISA, IHC-P, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Alternative HDAC1; RPD3L1; Histone deacetylase 1; HD1

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. Histone deacetylase 1 encoded by HDAC1 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.
Gene ID 3065
Alternative HDAC1; RPD3L1; Histone deacetylase 1; HD1
Others HDAC1 Polyclonal Antibody detects endogenous levels of HDAC1 protein.
Accession Q13547
Observed Band(KD) 55

Image & description

Fig. Western Blot analysis of various cells using HDAC1 Polyclonal Antibody diluted at 1:500.

Fig. Western Blot analysis of various cells using HDAC1 Polyclonal Antibody diluted at 1:500.

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