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GSK3β Polyclonal Antibody

GSK3β Polyclonal Antibody

Views(845) Publications(0) Catalog no(ABP57199)
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Specification

Product name GSK3β Polyclonal Antibody
Immunogen Recombinant Protein
Host Rabbit
Reactivity Mouse, Rat
Applications IHC-P, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:1000-1:2000), IHC-P (1:200-1:500).
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS, pH 7.4, containing 0.02% Sodium Azide as preservative and 50% Glycerol.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background The protein encoded by GSK3B (glycogen synthase kinase 3 beta) is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in GSK3B have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of GSK3B may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for GSK3B.
Gene ID 2932
Others The antibody detects endogenous GSK3β protein.
Accession P49841
Observed Band(KD) 46

Image & description

Fig.1. Western blot analysis of 1) Mouse Brain Tissue, 2) Mouse Heart Tissue, 3) Rat Brain Tissue, 4) Rat Heart Tissue using GSK3β Polyclonal Antibody. Secondary antibody (catalog#: A21020) was diluted at 1:20000.

Fig.1. Western blot analysis of 1) Mouse Brain Tissue, 2) Mouse Heart Tissue, 3) Rat Brain Tissue, 4) Rat Heart Tissue using GSK3β Polyclonal Antibody. Secondary antibody (catalog#: A21020) was diluted at 1:20000.

Fig.2. Immunohistochemical analysis of paraffin-embedded Mouse Lung Tissue using GSK3β Polyclonal Antibody.

Fig.2. Immunohistochemical analysis of paraffin-embedded Mouse Lung Tissue using GSK3β Polyclonal Antibody.

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