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GCSm-γ Polyclonal Antibody

GCSm-γ Polyclonal Antibody

Views(15) Publications(0) Catalog no(ABP51416)
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Specification

Product name GCSm-γ Polyclonal Antibody
Immunogen Synthesized peptide derived from the Internal region of human GCSm-γ
Host Rabbit
Reactivity Human, Monkey, Mouse, Rat
Applications ELISA, IHC-P, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Alternative GCLM; GLCLR; Glutamate--cysteine ligase regulatory subunit; GCS light chain; Gamma-ECS regulatory subunit; Gamma-glutamylcysteine synthetase regulatory subunit; Glutamate--cysteine ligase modifier subunit

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene ID 2730
Alternative GCLM; GLCLR; Glutamate--cysteine ligase regulatory subunit; GCS light chain; Gamma-ECS regulatory subunit; Gamma-glutamylcysteine synthetase regulatory subunit; Glutamate--cysteine ligase modifier subunit
Others GCSm-γ Polyclonal Antibody detects endogenous levels of GCSm-γ protein.
Accession P48507
Observed Band(KD) 31

Image & description

Fig.1. Western Blot analysis of various cells using GCSm-γ Polyclonal Antibody diluted at 1:1000.

Fig.1. Western Blot analysis of various cells using GCSm-γ Polyclonal Antibody diluted at 1:1000.

Fig.2. Western Blot analysis of COS7 cells using GCSm-γ Polyclonal Antibody diluted at 1:1000.

Fig.2. Western Blot analysis of COS7 cells using GCSm-γ Polyclonal Antibody diluted at 1:1000.

Fig.3. Western blot analysis of Mouse-kidney Mouse-brain lysate using GCSm-γ antibody. Antibody was diluted at 1:1000.

Fig.3. Western blot analysis of Mouse-kidney Mouse-brain lysate using GCSm-γ antibody. Antibody was diluted at 1:1000.

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