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Galectin-3 Monoclonal Antibody

Galectin-3 Monoclonal Antibody

Views(53) Publications(0) Catalog no(ABM0012)
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Specification

Product name Galectin-3 Monoclonal Antibody
Immunogen Synthetic Peptide
Host Mouse
Reactivity Human
Applications IF, IHC-P, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:2000), IF (1:100-1:200), IHC-P (1:200).
Clonality Monoclonal
Preparation method The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen
Alternative LGALS3; MAC2; Galectin-3; Gal-3; 35 kDa lectin; Carbohydrate-binding protein 35; CBP 35; Galactose-specific lectin 3; Galactoside-binding protein; GALBP; IgE-binding protein; L-31; Laminin-binding protein; Lectin L-29; Mac-2 antigen

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Molecular weight 26 KD
Storage buffer PBS, pH 7.4, containing 0.02% Sodium Azide as preservative and 50% Glycerol.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background LGALS3 encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. lectin, galactoside binding soluble 3 is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. lectin, galactoside binding soluble 3 can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. lectin, galactoside binding soluble 3 localizes to the extracellular matrix, the cytoplasm and the nucleus. lectin, galactoside binding soluble 3 plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. lectin, galactoside binding soluble 3 exhibits antimicrobial activity against bacteria and fungi. Alternate splicing results in multiple transcript variants
Gene ID 3958
Alternative LGALS3; MAC2; Galectin-3; Gal-3; 35 kDa lectin; Carbohydrate-binding protein 35; CBP 35; Galactose-specific lectin 3; Galactoside-binding protein; GALBP; IgE-binding protein; L-31; Laminin-binding protein; Lectin L-29; Mac-2 antigen
Others The antibody detects endogenous Galectin-3 proteins.
Accession P17931

Image & description

Fig.1. IHC-P staining of Human thyroid tissue paraffin-embedded, diluted at 1:200.

Fig.1. IHC-P staining of Human thyroid tissue paraffin-embedded, diluted at 1:200.

Fig.2. Western blot analysis of Hela, diluted at 1:3000.

Fig.2. Western blot analysis of Hela, diluted at 1:3000.

Fig.3. Immunofluorescence analysis of human lung cancer tissue. 1, Galectin-3 Monoclonal Antibody (red) was diluted at 1:200 (4°C, overnight). 2, Cy3 Labeled secondary antibody was diluted at 1:300 (room temperature, 50min). 3, Picture B: DAPI (blue) 10min. Picture A: Target. Picture B: DAPI. Picture C: merge of A+B.

Fig.3. Immunofluorescence analysis of human lung cancer tissue. 1, Galectin-3 Monoclonal Antibody (red) was diluted at 1:200 (4°C, overnight). 2, Cy3 Labeled secondary antibody was diluted at 1:300 (room temperature, 50min). 3, Picture B: DAPI (blue) 10min. Picture A: Target. Picture B: DAPI. Picture C: merge of A+B.

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