Login Register
English
0

Cart

$ 0

ERK 5 Polyclonal Antibody

ERK 5 Polyclonal Antibody

Views(347) Publications(0) Catalog no(ABP57196)
Datasheet Print Share Email Share
  • Specification
  • FAQ
  • Publications(0)
  • Comments(0)

Specification

Product name ERK 5 Polyclonal Antibody
Immunogen Recombinant Protein
Host Rabbit
Reactivity Human, Mouse, Rat
Applications IHC-P, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:1000-1:2000), IHC-P (1:200-1:500).
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS, pH 7.4, containing 0.02% Sodium Azide as preservative and 50% Glycerol.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background The protein encoded by MAPK7 (mitogen-activated protein kinase 7) is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of MAPK7 encoding two distinct isoforms have been reported.
Gene ID 5598
Others The antibody detects endogenous ERK 5 protein.
Accession Q13164
Observed Band(KD) 89-115

Image & description

Fig.1. Western blot analysis of 1) Hela, 2) 293T, 3) Mouse Skeletal Muscle, 4) Rat Kidney, 5) Rat Skeletal Muscle using ERK 5 Polyclonal Antibody. Secondary antibody (catalog#: A21020) was diluted at 1:20000.

Fig.1. Western blot analysis of 1) Hela, 2) 293T, 3) Mouse Skeletal Muscle, 4) Rat Kidney, 5) Rat Skeletal Muscle using ERK 5 Polyclonal Antibody. Secondary antibody (catalog#: A21020) was diluted at 1:20000.

Fig.2. Immunohistochemical analysis of paraffin-embedded human Breast caricnoma using ERK 5 Polyclonal Antibody.

Fig.2. Immunohistochemical analysis of paraffin-embedded human Breast caricnoma using ERK 5 Polyclonal Antibody.

This product has been cited in0publications

Reviews

There are no reviews yet.

Be the first to review “ERK 5 Polyclonal Antibody”