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DNA pol δ3 Polyclonal Antibody

DNA pol δ3 Polyclonal Antibody

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Specification

Product name DNA pol δ3 Polyclonal Antibody
Immunogen Synthesized peptide derived from the C-terminal region of human DNA pol δ3 at AA rangle: 380-460
Host Rabbit
Reactivity Human, Mouse, Rat
Applications ELISA, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Alternative POLD3; KIAA0039; DNA polymerase delta subunit 3; DNA polymerase delta subunit p66

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background POLD3 encodes the 66-kDa subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The DNA polymerase delta 3, accessory subunit plays a role in regulating the activity of DNA polymerase delta through interactions with other subunits and the processivity cofactor proliferating cell nuclear antigen (PCNA). Alternatively spliced transcript variants have been observed for this gene.
Gene ID 10714
Alternative POLD3; KIAA0039; DNA polymerase delta subunit 3; DNA polymerase delta subunit p66
Others DNA pol δ3 Polyclonal Antibody detects endogenous levels of DNA pol δ3 protein.
Accession Q15054
Observed Band(KD) 51

Image & description

Fig. Western Blot analysis of hela cells using DNA pol δ3 Polyclonal Antibody diluted at 1:500.

Fig. Western Blot analysis of hela cells using DNA pol δ3 Polyclonal Antibody diluted at 1:500.

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