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DiOC6(3)

DiOC6(3)

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Specification

Product name DiOC6(3)
CAS Number 53213-82-4
Molecular Formula C29H37IN2O2
Alternative 3,3'-Dihexyloxacarbocyanine

Product Properties

Formulation Orange-red solid
Features & Benefits • λEX/λEm: 484/501 nm (MeOH)
Molecular weight 572.53
Usage notes • Soluble in DMSO or DMF
Storage instructions Store at +4°C. The product can be stored for up to 12 months. Protect from light.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background 3,3'-Dihexyloxacarbocyanine (DiOC6(3)) is a lipophilic fluorescent dye with excitation/emission spectra of 484/501 nm, respectively. At high concentrations, DiOC6(3) accumulates in the endoplasmic reticulum (ER) and has been used to visualize ER in moss, yeast, and muscle cells. At low concentrations, DiOC6(3) accumulates in mitochondria and has been used to assess mitochondrial dislocations, fusion, and fission in living cells, as well as to visualize cellular apoptosis. DiOC6(3) can also be used to assess cell membrane potential, as depolarization directly correlates with increased fluorescence. DiOC6(3) photoexcitation inactivates intracellular organelle movement and inhibits microtubule polymerization in vitro.
Alternative 3,3'-Dihexyloxacarbocyanine

Image & description

Fig. DiOC6(3) structure formula

Fig. DiOC6(3) structure formula

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