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Collagen II Mouse Monoclonal Antibody (8F6)

Collagen II Mouse Monoclonal Antibody (8F6)

Views(43) Publications(0) Catalog no(ABM40365)
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Specification

Product name Collagen II Mouse Monoclonal Antibody (8F6)
Immunogen Synthetic Peptide of Collagen II
Host Mouse
Reactivity Human, Mouse, Rat
Applications IHC-P
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:50-1:200).
Clonality Monoclonal
Preparation method The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen
Alternative Collagen alpha-1(II) chain; Alpha-1 type II collagen

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS, pH 7.4, containing 0.02% Sodium Azide as preservative and 50% Glycerol.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background COL2A1 (collagen type II alpha 1 chain) encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in COL2A1 are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for COL2A1.
Gene ID 1280
Alternative Collagen alpha-1(II) chain; Alpha-1 type II collagen
Others The antibody detects endogenous Collagen II protein .
Accession P02458
Observed Band(KD) 142

Image & description

Fig. Immunohistochemical analysis of paraffin-embedded Human Lung Carcinoma Tissue using Collagen II Mouse mAb diluted at 1:200.

Fig. Immunohistochemical analysis of paraffin-embedded Human Lung Carcinoma Tissue using Collagen II Mouse mAb diluted at 1:200.

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