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Catenin-α E/N Polyclonal Antibody

Catenin-α E/N Polyclonal Antibody

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Specification

Product name Catenin-α E/N Polyclonal Antibody
Immunogen Synthesized peptide derived from the C-terminal region of human Catenin-α E/N at AA range: 830-910
Host Rabbit
Reactivity Human, Mouse, Rat
Applications ELISA, IF, IHC-P, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Alternative CTNNA1; Catenin alpha-1; Alpha E-catenin; Cadherin-associated protein; Renal carcinoma antigen NY-REN-13; CTNNA2; CAPR; Catenin alpha-2; Alpha N-catenin; Alpha-catenin-related protein

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background CTNNA1 encodes a member of the catenin family of proteins that play an important role in cell adhesion process by connecting cadherins located on the plasma membrane to the actin filaments inside the cell. The encoded mechanosensing protein (catenin alpha 1) contains three vinculin homology domains and undergoes conformational changes in response to cytoskeletal tension, resulting in the reconfiguration of cadherin-actin filament connections. Certain mutations in this gene cause butterfly-shaped pigment dystrophy.
Gene ID 1495/1496
Alternative CTNNA1; Catenin alpha-1; Alpha E-catenin; Cadherin-associated protein; Renal carcinoma antigen NY-REN-13; CTNNA2; CAPR; Catenin alpha-2; Alpha N-catenin; Alpha-catenin-related protein
Others Catenin-α E/N Polyclonal Antibody detects endogenous levels of Catenin-α E/N protein.
Accession P35221/P26232
Observed Band(KD) 100

Image & description

Fig. Western Blot analysis of various cells using Catenin-α E/N Polyclonal Antibody diluted at 1:500.

Fig. Western Blot analysis of various cells using Catenin-α E/N Polyclonal Antibody diluted at 1:500.

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