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c-Fos Monoclonal Antibody

c-Fos Monoclonal Antibody

Views(428) Publications(0) Catalog no(ABM0065)
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Specification

Product name c-Fos Monoclonal Antibody
Immunogen Recombinant Protein
Host Mouse
Reactivity Human, Mouse, Rat
Applications IHC-P, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300).
Clonality Monoclonal
Preparation method The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Molecular weight 62 KD
Storage buffer PBS, pH 7.4, containing 0.02% Sodium Azide as preservative and 50% Glycerol.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background The Fos gene family consists of 4 members: fOS (Fos proto-oncogene, AP-1 transcription factor subunit), FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.
Gene ID 2353
Others The antibody detects c-Fos.
Accession P01100

Image & description

Fig.1. Western blot analysis of 1) Hela, 2) 293T, 3) Mouse Brain Tissue, 4) Rat Brain Tissue with c-Fos Mouse mAb diluted at 1:2000.

Fig.1. Western blot analysis of 1) Hela, 2) 293T, 3) Mouse Brain Tissue, 4) Rat Brain Tissue with c-Fos Mouse mAb diluted at 1:2000.

Fig.2. Immunohistochemical analysis of paraffin-embedded Human Breast Caricnoma using c-FosMouse mAb diluted at 1:200.

Fig.2. Immunohistochemical analysis of paraffin-embedded Human Breast Caricnoma using c-FosMouse mAb diluted at 1:200.

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